• High-Grade Cervical Intraepithelial Neoplasia (CIN) Associates with Increased Proliferation and Attenuated Immune Signaling 

      Øvestad, Irene Tveiterås; Engesæter, Birgit Øvstebø; Halle, Mari Kyllesø; Akbari, Saleha; Bicskei, Beatrix; Lapin, Morten; Austdal, Marie; Janssen, Emiel; Krakstad, Camilla; Lillesand, Melinda; Nordhus, Marit; Munk, Ane Cecilie Dæhli; Gudlaugsson, Einar (Journal article; Peer reviewed, 2021)
      Implementation of high-risk human papilloma virus (HPV) screening and the increasing proportion of HPV vaccinated women in the screening program will reduce the percentage of HPV positive women with oncogenic potential. ...
    • Liquid Biopsies in Solid Cancers: Implementation in a Nordic Healthcare System 

      Nordgård, Oddmund; Forthun, Rakel Brendsdal; Lapin, Morten; Grønberg, Bjørn Henning; Kalland, Karl Henning; Kopperud, Reidun Kristin; Thomsen, Liv Cecilie Vestrheim; Tjensvoll, Kjersti; Gilje, Bjørnar; Gjertsen, Bjørn Tore; Hovland, Randi (Journal article; Peer reviewed, 2021)
      Liquid biopsies have emerged as a potential new diagnostic tool, providing detailed information relevant for characterization and treatment of solid cancers. We here present an overview of current evidence supporting the ...
    • Novel hybridization- and tag-based error-corrected method for sensitive ctDNA mutation detection using ion semiconductor sequencing 

      Tjensvoll, Kjersti; Lapin, Morten; Gilje, Bjørnar; Garresori, Herish; Oltedal, Satu; Forthun, Rakel Brendsdal; Molven, Anders; Rozenholc, Yves; Nordgård, Oddmund (Journal article; Peer reviewed, 2022)
      Circulating tumor DNA (ctDNA) analysis has emerged as a clinically useful tool for cancer diagnostics and treatment monitoring. However, ctDNA detection is complicated by low DNA concentrations and technical challenges. ...